BDBM11979 5-[(3-carboxy-4-hydroxyphenyl)methyl]-2-hydroxybenzoic acid::CHEMBL115145::MgrA inhibitor, 1::chemical diversity library compound 4

SMILES OC(=O)c1cc(Cc2ccc(O)c(c2)C(O)=O)ccc1O

InChI Key InChIKey=JWQFKVGACKJIAV-UHFFFAOYSA-N

Data  1 KI  18 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 11979   

TargetGenome polyprotein(Dengue virus type 2)
University Of Basel

Curated by ChEMBL
LigandPNGBDBM11979(5-[(3-carboxy-4-hydroxyphenyl)methyl]-2-hydroxyben...)
Affinity DataIC50:  1.52E+3nMAssay Description:Inhibition of Dengue virus type 2 NS5 RNA methyltransferase SAM siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus type 2)
University Of Basel

Curated by ChEMBL
LigandPNGBDBM11979(5-[(3-carboxy-4-hydroxyphenyl)methyl]-2-hydroxyben...)
Affinity DataIC50:  9.46E+3nMAssay Description:Inhibition of Dengue virus type 2 NS5 RNA methyltransferase SAM site with 0.1 % TX100More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus type 2)
University Of Basel

Curated by ChEMBL
LigandPNGBDBM11979(5-[(3-carboxy-4-hydroxyphenyl)methyl]-2-hydroxyben...)
Affinity DataIC50:  6.22E+3nMAssay Description:Inhibition of Dengue virus type 2 NS5 RNA methyltransferase by spin-down assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus type 2)
University Of Basel

Curated by ChEMBL
LigandPNGBDBM11979(5-[(3-carboxy-4-hydroxyphenyl)methyl]-2-hydroxyben...)
Affinity DataIC50:  3.16E+3nMAssay Description:Inhibition of Dengue virus type 2 NS5 RNA methyltransferase at 8 nM enzyme concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus type 2)
University Of Basel

Curated by ChEMBL
LigandPNGBDBM11979(5-[(3-carboxy-4-hydroxyphenyl)methyl]-2-hydroxyben...)
Affinity DataIC50:  7.14E+3nMAssay Description:Inhibition of Dengue virus type 2 NS5 RNA methyltransferase at 80 nM enzyme concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed